Hydrochloric Acid → HCID 70503709, compound

HRID 1154023Notes

Reaction equation

HRID 1154023 reaction equation
[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]2[C:20]3[CH2:19][CH2:18][CH2:17][CH2:16][C:15]=3[C:14]3=[N:21][N:22]=[CH:23][N:13]3[N:12]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[ClH:24]>C(Cl)Cl>[ClH:24].[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]2[C:20]3[CH2:19][CH2:18][CH2:17][CH2:16][C:15]=3[C:14]3=[N:21][N:22]=[CH:23][N:13]3[N:12]=2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[ClH:24].[ClH:24].[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]2[C:20]3[CH2:19][CH2:18][CH2:17][CH2:16][C:15]=3[C:14]3=[N:21][N:22]=[CH:23][N:13]3[N:12]=2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13365605HCID 13365605, compound

Product 1

HCID 70503709HCID 70503709, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The amine obtained above was dissolved in methylene chloride and then treated with an excess of ethereal hydrogen chloride to give 6-[4-(1-pyrrolidinyl)butylamino]-7,8,9,10-tetrahydro-1,2,4-triazolo[3,4-a]phthalazine sesquihydrochloride melting at about 237°-238° C.

Sources & evidence

ORD record
ord-2b9683180833409ebef2119eb6405377
Source dataset
uspto-grants-1984_12
Patent number
US04487930

Reaction notes

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