HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70515299, compound → HCID 13774859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70515299 | HCID 70515299 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 13774859 | HCID 13774859 | 66% |
Reaction Steps
A solution of 16.9 g of tert.butyl 2-(2-ethoxycarbonylacetyl)hexahydropyridazine-3-carboxylate in 350ml of glacial acetic acid was heated at 100° C. for 1.5 hours. Evaporation gave an oil which was chromatographed on silica gel to yield 9.45 g (66%)of tert.butyl hexahydro-1,3-dioxo-1H-pyrazolo[1,2-a]pyridazine-5-carboxylate in the form of a pale yellow solid having a melting point of 121°-122° C. (from chloroform/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04487929 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-459ac8676d9543c79fd265222594acdb |
| Source note | uspto-grants-1984_12 |