Hydrochloric Acid → HCID 178479216, compound

HRID 1154119Notes

Reaction equation

HRID 1154119 reaction equation
C([NH:4][CH2:5][CH2:6][CH2:7][N:8]1[C:12]([SH:13])=[N:11][N:10]=[N:9]1)(=O)C.[ClH:14]>>[ClH:14].[NH2:4][CH2:5][CH2:6][CH2:7][N:8]1[C:12]([SH:13])=[N:11][N:10]=[N:9]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178474793HCID 178474793, compound

Product 1

HCID 178479216HCID 178479216, compound

Procedure

A mixture of 1-(3-acetamidopropyl)-1H-tetrazole-5-thiol (85 g) and 6N hydrochloric acid (1 l) was refluxed for 75 minutes under stirring. The reaction mixture was concentrated in vacuo and precipitates were collected by filtration and washed with hexane and diethyl ether to give 1-(3-aminopropyl)-1H-tetrazole-5-thiol hydrochloride (67.15 g).

Workup

  1. temperaturewas refluxed for 75 minutes
  2. concentrationThe reaction mixture was concentrated in vacuo
  3. customprecipitates
  4. filtrationwere collected by filtration
  5. washwashed with hexane and diethyl ether

Sources & evidence

ORD record
ord-e626872f8af34a81917dbcb23313e739
Source dataset
uspto-grants-1984_12
Patent number
US04487767

Reaction notes

Loading…