Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2,3,5-Trimethylanisole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | 2,3,5-Trimethylphenol | HCID 12769 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 2,3,5-Trimethylanisole | HCID 88555 | — |
반응 단계
In 100 ml of DMSO were dissolved 10 g of 2,3,5-trimethylphenol and 10.4 ml of methyl iodide. Under ice-cooling, 5.6 g of 60% sodium hydride in oil was added, and the mixture was stirred at room temperature for 10 hours. After addition of water, the extraction with ether was carried out. The ether layer was washed with water and dried over anhydrous sodium sulfate. Removal of the solvent by distillation leaves the oily substance. Yield 12.9 g (quantitative)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04487726 |
| 출처 데이터셋 | uspto-grants-1984_12 |
| ORD ID | ord-2189fa23ece643879df3626b0fc3c881 |
| 출처 메모 | uspto-grants-1984_12 |