反应详情

To 51.8 g. (0.68 mole) of ammonium thiocyanate in 300 ml acetone is added 86.8 g (0.62 mole) of benzoyl chloride. The reaction mixture is refluxed for about 5 min. and then 100 g (0.62 mole) of 2,6-dichloroaniline in 200 ml acetone is added at a rate to maintain reflux. The mixture is refluxed for 11/2 hours, cooled, poured into 11/2 liters of ice and water, filtered to obtain 1-(2,6-dichlorophenyl)-3-benzoylthiourea.

1. temperatureThe reaction mixture is refluxed for about 5 min.
2. temperatureto maintain
3. temperaturereflux
4. temperatureThe mixture is refluxed for 11/2 hours
5. temperaturecooled
6. filtrationfiltered