Chloride → Tert-butyl 4-[1-(2-pyrrolidin-1-ylethyl)-4-tetrahydropyran-4-yl-imidazol-2-yl]piperidine-1-carboxylate
Reaction equation
[CH3:38][S:39](=[O:40])[CH3:41].[Cl-:29].[Cl:30][CH2:31][CH2:32][NH+:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[I-:28].[K+:26].[Na+:27].[O:1]1[CH2:2][CH2:3][CH:4]([c:7]2[n:8][c:9]([CH:12]3[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[nH:10][cH:11]2)[CH2:5][CH2:6]1.[OH-:25]>>[O:1]1[CH2:2][CH2:3][CH:4]([c:7]2[n:8][c:9]([CH:12]3[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[n:10]([CH2:31][CH2:32][N:33]3[CH2:34][CH2:35][CH2:36][CH2:37]3)[cH:11]2)[CH2:5][CH2:6]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-0591a92d7a7a440b981fe7867c0a9cb0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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