反应详情

To a mixture of 11 g (0.05 mole) of 1-(2,6-dichlorophenyl)thiourea and 10 ml of xylene is added 5 g of t-butylisocyanate (0.05 mole) and the mixture is refluxed for 2 hours. The reaction product is cooled, triturated with heptane and filtered. Recrystallization from 1:1 isopropanol/water results in 1-(2,6-dichlorophenyl)-3-(t-butylcarbamyl)thiourea.

1. temperaturethe mixture is refluxed for 2 hours
2. temperatureThe reaction product is cooled
3. customtriturated with heptane
4. filtrationfiltered
5. customRecrystallization from 1:1 isopropanol/water
6. customresults in 1-(2,6-dichlorophenyl)-3-(t-butylcarbamyl)thiourea