HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorobenzo(b)thiophene-2-carbonyl chloride → 3-Chloro-N-[2-(1H-imidazol-1-yl)ethyl]benzo[b]thiophene-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorobenzo(b)thiophene-2-carbonyl chloride | HCID 519898 | — |
| Reactant | 2-(Imidazol-1-yl)-ethylamine dihydrochloride | HCID 12377913 | — |
| Product | 3-Chloro-N-[2-(1H-imidazol-1-yl)ethyl]benzo[b]thiophene-2-carboxamide | HCID 13371083 | — |
Reaction Steps
A 1.47 g. portion of 1H-imidazole-1-ethanamine dihydrochloride was reacted with 3-chloro-benzo[b]thiophene-2-carbonyl chloride as described in Example 1, giving 0.75 g. of the desired product, m.p. 132°-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04489089 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-ef45f4628b9a4d17af341ec4b9d2a7f7 |
| Source note | uspto-grants-1984_12 |