HCID 13385556, compound → HCID 13385557, compound

HRID 1154522Notes

Reaction equation

HRID 1154522 reaction equation
C([O:5][C:6]([CH2:8][NH:9][C:10]([C:12]1[O:13][C:14]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:15]=2[N:16]=1)=[O:11])=[O:7])(C)(C)C>FC(F)(F)C(O)=O>[C:6]([CH2:8][NH:9][C:10]([C:12]1[O:13][C:14]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:15]=2[N:16]=1)=[O:11])([OH:7])=[O:5]

Participants

3

Reactant 1

HCID 13385556HCID 13385556, compound

Product 1

HCID 13385557HCID 13385557, compoundYield 118%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Compound from Example 2 (3 g) in 10 ml of trifluoroacetic acid was kept at room temperature overnight. The solvent was removed and ether was added to give 2.9 g of product; mp 222°-224° (dec.).

Workup

  1. customThe solvent was removed
  2. additionether was added

Sources & evidence

ORD record
ord-af85632d6ec34e6998f7c0ab2fc42e25
Source dataset
uspto-grants-1984_12
Patent number
US04490373

Reaction notes

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