HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Dimethylamino)-1-propanol → N,N1-Dimethyl-S-(3-dimethylaminopropyl)isothiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Dimethylamino)-1-propanol | HCID 76646 | — |
| Reactant | 1,1-Dimethyl-2-thiourea | HCID 3034192 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | N,N1-Dimethyl-S-(3-dimethylaminopropyl)isothiourea | HCID 86120174 | — |
Reaction Steps
A mixture of 3-dimethylaminopropanol (10.3 g), N,N1 -dimethylthiourea (10.4 g) and aqueous hydrobromic acid (48%, 60 ml) was boiled under reflux for 18 hours and evaporated to dryness. The residue was recrystallised from ethanol to give the dihydrobromide of the title compound m.p. 173°-174°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04490387 |
| Source dataset | uspto-grants-1984_12 |
| ORD ID | ord-48ce41456d97414c89248eac0a9d6597 |
| Source note | uspto-grants-1984_12 |