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HRID1154782

反应详情

EQUATION

反应方程式

HRID 1154782 的结构方程式

REACTANTS

反应物

1
结构：CC=C1C[C@H]2[C@@H]3CCc4cc(OC)ccc4[C@H]3CC[C@]2(C)C1=O
HCID54221529

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@H]1C[C@H]2[C@@H]3CCc4cc(OC)ccc4[C@H]3CC[C@]2(C)C1=O
HCID22818353

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A suspension of 2.0 g. of 16-ethylidene-3-methoxy-1,3,5(10)-estratrien-17-one in 80 ml. of ethanol is combined with 200 mg. of 10% palladium-charcoal and hydrogenated for 60 minutes at room temperature under normal pressure. After removing the catalyst by filtration and concentration of the reaction product, 2.0 g. of 16β-ethyl-3-methoxy-1,3,5(10)-estratrien-17-one is obtained, m.p. 93°-94° C.

WORKUP

后处理

  1. additionA suspension of 2.0 g
  2. customAfter removing the catalyst
  3. filtrationby filtration and concentration of the reaction product, 2.0 g