HuagongsheHuagongshe Chemistry Print Report · For research reference only
16-Ethylidene-3-methoxy-1,3,5(10)-estratrien-17-one → 16beta-Ethyl-3-methoxy-1,3,5(10)-estratrien-17-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 16-Ethylidene-3-methoxy-1,3,5(10)-estratrien-17-one | HCID 54221529 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 16beta-Ethyl-3-methoxy-1,3,5(10)-estratrien-17-one | HCID 22818353 | — |
Reaction Steps
A suspension of 2.0 g. of 16-ethylidene-3-methoxy-1,3,5(10)-estratrien-17-one in 80 ml. of ethanol is combined with 200 mg. of 10% palladium-charcoal and hydrogenated for 60 minutes at room temperature under normal pressure. After removing the catalyst by filtration and concentration of the reaction product, 2.0 g. of 16β-ethyl-3-methoxy-1,3,5(10)-estratrien-17-one is obtained, m.p. 93°-94° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04298538 |
| Source dataset | uspto-grants-1981_11 |
| ORD ID | ord-55f2704828c44f909ce30d3b8710b80c |
| Source note | uspto-grants-1981_11 |