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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1155059Generated: October 31, 2026

HCID 178469125, compound → 4-Hydroxy-2-(trifluoromethyl)quinoline-3-carboxylic acid

https://huagongshe.com/reaction/1155059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178469125HCID 178469125—
SolventDiethyl EtherHCID 3283—
Product4-Hydroxy-2-(trifluoromethyl)quinoline-3-carboxylic acidHCID 17852453697.2%

Reaction Steps

Using the procedure of Step E of Example 8, 30 g of the product of Step D were reacted to obtain without ether purification 26.3 g of 2-trifluoromethyl-4-hydroxy-3-quinoline-carboxylic acid melting at 262° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04299831
Source datasetuspto-grants-1981_11
ORD IDord-26d1f82ff02340d5bfcadec49ef05996
Source noteuspto-grants-1981_11