Anthralin → Butantrone

HRID 1155143Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1155143
[C:1](Cl)(=[O:5])[CH2:2][CH2:3][CH3:4].[CH:7]1[CH:8]=[C:9]2[CH2:23][C:17]3[CH:18]=[CH:19][CH:20]=[C:21]([OH:22])[C:16]=3[C:14](=[O:15])[C:10]2=[C:11]([OH:13])[CH:12]=1>C1C=CC=CC=1.N1C=CC=CC=1>[OH:22][C:21]1[C:16]2[C:14](=[O:15])[C:10]3[C:9](=[CH:8][CH:7]=[CH:12][C:11]=3[OH:13])[CH:23]([C:1](=[O:5])[CH2:2][CH2:3][CH3:4])[C:17]=2[CH:18]=[CH:19][CH:20]=1

Komponenten

5

Edukt 2

HCID 2202AnthralinHCID 8855Butyryl chloride

Produkt 1

HCID 53271Butantrone

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 241BenzeneLösungsmittelHCID 1049PyridineLösungsmittel

Versuchsvorschrift

28.6 g (0.27 moles) butyryl chloride is added, while stirring, to a mixture containing 50.9 g (0.225 moles) anthraline in 1575 ml benzene and 27.5 ml pyridine. The reaction mixture is cooked using a return condenser for 10 hours while stirring. The solution is filtered and the filrate is evaporated dry under a lowered pressure. The residue is crystallized out from acetic acid. Yield 17.0 g (25.5% of the theoretical).

Aufarbeitung

  1. customfor 10 hours
  2. stirringwhile stirring
  3. filtrationThe solution is filtered
  4. customthe filrate is evaporated
  5. customdry under a lowered pressure
  6. customThe residue is crystallized out from acetic acid

Quellen und Nachweise

ORD-Eintrag
ord-594df806e7d847518c9771e4a40e96e5
Quelldatensatz
uspto-grants-1981_11
Patentnummer
US04299846

Notizen zur Reaktion

Wird geladen…