Thionyl Chloride → HCID 13100663, compound

HRID 1155205Notes

Reaction equation

HRID 1155205 reaction equation
[Br:1][C:2]([Br:9])([Br:8])[CH2:3][CH2:4][C:5](O)=[O:6].S(Cl)([Cl:12])=O>CN(C)C=O>[Br:1][C:2]([Br:9])([Br:8])[CH2:3][CH2:4][C:5]([Cl:12])=[O:6]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 131006624,4,4-Tribromobutanoic acid

Product 1

HCID 13100663HCID 13100663, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

324.8 g (1.0 mol) of 4,4,4-tribromobutyric acid are warmed with 600 g of thionyl chloride and 1 ml of dimethylformamide, first for 2 hours at 40° C. and then for 3 hours at 75° C. The excess thionyl chloride is then distilled off and the residue is rectified under a high vacuum. 326.0 g (95% of theory) of 4,4,4-tribromobutyric acid chloride with a boiling point of 71° to 73° C./0.05 mm Hg are obtained.

Workup

  1. distillationThe excess thionyl chloride is then distilled off

Sources & evidence

ORD record
ord-88fcb741c8a6418d92e314167405e300
Source dataset
uspto-grants-1981_11
Patent number
US04299967

Reaction notes

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