Anthranilic Acid → 2-Hydroxyquinoline

Participants

Reaction Steps

The required 1-H-4-quinolones for the above reactions were prepared in a similar way to that described in Example 6. The appropriate anthranilic acid was converted to the benzoxazine X which was then converted to the β-ketosulphoxide XI which then underwent ring closure to give the 1-H-quinolone XII ##STR11##

Provenance & Evidence