Hydroxyamine hydrochloride → HCID 21764113, compound

HRID 1155663Notes

Reaction equation

HRID 1155663 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:13][CH:12]3[C:14](=O)[CH:9]([CH2:10][CH2:11]3)[CH2:8][C:7]=2[CH:16]=1.Cl.[NH2:18][OH:19]>C(O)C.N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:13][CH:12]3[C:14](=[N:18][OH:19])[CH:9]([CH2:10][CH2:11]3)[CH2:8][C:7]=2[CH:16]=1

Participants

5

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 13026444HCID 13026444, compound

Product 1

HCID 21764113HCID 21764113, compoundYield 86.9%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 1049PyridineSolvent

Procedure

2-Methoxy-11-oxo-5,6,7,8,9,10-hexahydro-6,9-methanobenzocyclooctene (20.0 g; 0.1 mole) is reacted with hydroxylamine hydrochloride (20.0 g; 0.29 mole) in ethanol (100 ml) and pyridine (100 ml) to yield 20.1 g of the title compound.

Sources & evidence

ORD record
ord-a670b1f01f884170b5575dafb255b606
Source dataset
uspto-grants-1982_06
Patent number
US04332810

Reaction notes

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