1,1'-Carbonyldiimidazole → HCID 178466816, compound

HRID 1155701Notes

Reaction equation

HRID 1155701 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][C:13]([N:16]([CH2:19][CH3:20])[CH2:17][CH3:18])=[CH:12][CH:11]=2)[N:7]=[C:6]([C:21](O)=[O:22])[CH:5]=1)[CH3:2].C(N1C=CN=C1)(N1C=CN=C1)=O.[NH2:36][C:37]1[NH:41][N:40]=[N:39][N:38]=1>>[NH:38]1[C:37]([NH:36][C:21]([C:6]2[CH:5]=[C:4]([O:3][CH2:1][CH3:2])[CH:9]=[C:8]([C:10]3[CH:11]=[CH:12][C:13]([N:16]([CH2:19][CH3:20])[CH2:17][CH3:18])=[CH:14][CH:15]=3)[N:7]=2)=[O:22])=[N:41][N:40]=[N:39]1

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 20537520HCID 20537520, compoundHCID 178509299HCID 178509299, compound

Product 1

HCID 178466816HCID 178466816, compoundYield 76.5%

Procedure

In the same manner as described in Example 1-(1), 4-ethoxy-6-(4-diethylaminophenyl)-2-pyridinecarboxylic acid (0.56 g), carbonyldiimidazole (0.32 g) and 5-aminotetrazole (0.17 g) are reacted to give N-(5-tetrazolyl)-4-ethoxy-6-(4-diethylaminophenyl)-2-pyridinecarboxamide (0.52 g). M.P. 228°-230° C. (decomp.) (recrystallized from dimethylformamide-ethanol)

Sources & evidence

ORD record
ord-1e4b2b9fd6924487b8bd7dc448d29843
Source dataset
uspto-grants-1982_06
Patent number
US04332809

Reaction notes

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