1,1'-Carbonyldiimidazole → HCID 178492683, compound

HRID 1155704Notes

Reaction equation

HRID 1155704 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[CH:10]=2)[N:6]=[C:5]([C:18]([OH:20])=O)[CH:4]=1.C(N1C=CN=C1)(N1C=CN=C1)=O.[NH2:33][C:34]1[NH:38][N:37]=[N:36][N:35]=1>>[NH:35]1[C:34]([NH:33][C:18]([C:5]2[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[C:7]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[CH:10]=3)[N:6]=2)=[O:20])=[N:38][N:37]=[N:36]1

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 12811142HCID 12811142, compoundHCID 178509299HCID 178509299, compound

Product 1

HCID 178492683HCID 178492683, compoundYield 62.3%

Procedure

In the same manner as described in Example 1-(1), 4-methoxy-6-(3-nitrophenyl)-2-pyridinecarboxylic acid (0.4 g), carbonyldiimidazole (0.22 g) and 5-aminotetrazole (0.15 g) are reacted to give N-(5-tetrazolyl)-4-methoxy-6-(3-nitrophenyl)-2-pyridinecarboxamide (0.31 g). M.P. 269°-272.5° C. (decomp.) (wetted from about 250° C.) (recrystallized from dimethylformamide-ethyl acetate)

Sources & evidence

ORD record
ord-f680d19033a449779820ce426bf792f2
Source dataset
uspto-grants-1982_06
Patent number
US04332809

Reaction notes

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