Thionyl Chloride → HCID 178522662, compound

HRID 1155705Notes

Reaction equation

HRID 1155705 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[N:15]=[C:14]([C:16]([OH:18])=O)[CH:13]=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].S(Cl)(Cl)=O.[NH2:23][C:24]1[NH:28][N:27]=[N:26][N:25]=1>>[NH:25]1[C:24]([NH:23][C:16]([C:14]2[CH:13]=[CH:12][CH:11]=[C:10]([C:6]3[CH:7]=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=3)[N:15]=2)=[O:18])=[N:28][N:27]=[N:26]1

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 128111286-(3-Nitrophenyl)pyridine-2-carboxylic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178522662HCID 178522662, compoundYield 96.1%

Procedure

In the same manner as described in Example 13-(1), 6-(3-nitrophenyl)-2-pyridinecarboxylic acid (4.0 g), thionyl chloride (12 ml) and 5-aminotetrazole (1.54 g) are reacted to give N-(5-tetrazolyl)-6-(3-nitrophenyl)-2-pyridinecarboxamide (4.9 g). M.P. 275°-279° C. (decomp.)

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-99248d2532d54b98bc8e36817c88b939
Source dataset
uspto-grants-1982_06
Patent number
US04332809

Reaction notes

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