Isobutyric Acid → (Methylthio)methyl 2-methylpropanoate

HRID 1155720Notes

Reaction equation

[C:1]([OH:6])(=[O:5])[CH:2]([CH3:4])[CH3:3].[CH3:7][S:8][CH2:9]Cl.C(N(CC)CC)C>>[C:1]([O:6][CH2:7][S:8][CH3:9])(=[O:5])[CH:2]([CH3:4])[CH3:3]

Participants

Reactant 3

HCID 6590Isobutyric Acid

HCID 8471Triethylamine

HCID 16916Chloromethyl methyl sulfide

Product 1

HCID 20481371(Methylthio)methyl 2-methylpropanoate

Procedure

This product was prepared according to the procedure described in Example 1, by reacting isobutyric acid with chloromethyl methyl sulfide in the presence of one equivalent of triethylamine; b.p. 64° C./12 mm Hg, nD20 1.4470.

Workup

customThis product was prepared

Sources & evidence

ORD record: ord-bd3e082e8ecd4a479789601898ea790b
Source dataset: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04332829

Reaction notes

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