Triethylamine → (Methylsulfanyl)methyl 3-methylbutanoate

HRID 1155722Notes

Reaction equation

[C:1]([OH:7])(=[O:6])[CH2:2][CH:3]([CH3:5])[CH3:4].[CH3:8][S:9][CH2:10]Cl.C(N(CC)CC)C>>[C:1]([O:7][CH2:8][S:9][CH3:10])(=[O:6])[CH2:2][CH:3]([CH3:5])[CH3:4]

Participants

Reactant 3

HCID 8471Triethylamine

HCID 10430Isovaleric Acid

HCID 16916Chloromethyl methyl sulfide

Product 1

HCID 3018316(Methylsulfanyl)methyl 3-methylbutanoate

Procedure

This product was prepared according to the procedure described in Example 1, by reacting isovaleric acid with chloromethyl methyl sulfide in the presence of one equivalent of triethylamine; b.p. 78°-79° C./12 mm Hg, nD20 1.4496.

Workup

customThis product was prepared

Sources & evidence

ORD record: ord-31a4b19bed464ea5b7e25deb97eed335
Source dataset: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04332829

Reaction notes

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