Hydrochloric Acid → HCID 20536168, compound

HRID 1155935Notes

Reaction equation

HRID 1155935 reaction equation
[NH2:1][CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][C:6]=1[NH:12]C(=O)C.[ClH:16]>>[ClH:16].[ClH:16].[ClH:16].[NH2:1][CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][C:6]=1[NH2:12]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20536173HCID 20536173, compound

Product 1

HCID 20536168HCID 20536168, compound

Procedure

2 g. (0.0087 mol) of 2-acetylamino-4-aminophenyl β-aminoethyl ether are heated in 5 cm3 of hydrochloric acid for 20 minutes on a boiling waterbath. On cooling, the trihydrochloride crystallizes. The product is filtered off, washed with ether and dried in vacuo over KOH. It melts at 280° C. with decomposition.

Workup

  1. temperatureOn cooling
  2. customthe trihydrochloride crystallizes
  3. filtrationThe product is filtered off
  4. washwashed with ether
  5. dry with materialdried in vacuo over KOH

Sources & evidence

ORD record
ord-e28ea9ffc41a4b77a2020f74e6b8754d
Source dataset
uspto-grants-1982_06
Patent number
US04333730

Reaction notes

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