Hydrochloric Acid → HCID 20536175, compound

HRID 1155938Notes

Reaction equation

HRID 1155938 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][C:7]=1[NH:13]C(=O)C.[ClH:17]>>[ClH:17].[ClH:17].[ClH:17].[NH2:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][C:7]=1[NH2:13]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20536174HCID 20536174, compound

Product 1

HCID 20536175HCID 20536175, compound

Procedure

0.00806 mol (1.8 g) of 2-acetylamino-4-aminophenyl γ-aminopropyl ether is heated in 4.5 cm3 of concentrated hydrochloric acid for one hour on a boiling waterbath. On cooling, the expected product precipitates. After being filtered off, washed with ethyl ether and dried in vacuo over KOH, it melts at 260° C. with decomposition. A potentiometric determination is carried out in water by means of N/10 NaOH and the following result is obtained:

Workup

  1. temperatureOn cooling
  2. customthe expected product precipitates
  3. filtrationAfter being filtered off
  4. washwashed with ethyl ether
  5. dry with materialdried in vacuo over KOH, it melts at 260° C. with decomposition
  6. customthe following result
  7. customis obtained

Sources & evidence

ORD record
ord-8f612831b7a746b38dc847f26aa7f154
Source dataset
uspto-grants-1982_06
Patent number
US04333730

Reaction notes

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