Hydrochloric Acid → Piperidine, 1-methyl-4-phenoxy-4-(phenylmethyl)-

HRID 1156030Notes

Reaction equation

HRID 1156030 reaction equation
Cl.N[C:3]1[CH:23]=[CH:22][C:6]([O:7][C:8]2([CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH2:9]2)=[CH:5][CH:4]=1>C(O)C>[CH2:15]([C:8]1([O:7][C:6]2[CH:22]=[CH:23][CH:3]=[CH:4][CH:5]=2)[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 3060393Benzenamine, 4-((1-methyl-4-(phenylmethyl)-4-piperidinyl)oxy)-

Product 1

HCID 3060395Piperidine, 1-methyl-4-phenoxy-4-(phenylmethyl)-

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

[as the hydrochloride of m.p. 197° to 198° C. (from ethanol)] from 4-(4-aminophenoxy)-4-benzyl-1-methylpiperidine.

Sources & evidence

ORD record
ord-679d13e4097b4e7aaf8180a78c64aedd
Source dataset
uspto-grants-1982_06
Patent number
US04333942

Reaction notes

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