反应详情

3 Grams of α-oximinophenylacetic acid is dissolved in 9 ml of 37% formaldehyde containing a few drops of sulfuric acid. This is stirred overnight at RT, extracted with 3:1 ether:hexane, washed with brine, dried over sodium sulfate, stripped and distilled to yield the final product α-oxophenylacetic acid, b.p.=138°-141°/3.3 mm.

1. extractionextracted with 3:1 ether
2. washhexane, washed with brine
3. dry with materialdried over sodium sulfate
4. distillationdistilled