Methyl bromoacetate → Methyl (6,7-dichloro-1-oxo-2-phenyl-5-indanyloxy)acetate

HRID 1156186Notes

Reaction equation

[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][CH:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:8]2=[O:12])=[CH:4][C:3]=1[OH:19].Br[CH2:21][C:22]([O:24][CH3:25])=[O:23]>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][CH:7]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:8]2=[O:12])=[CH:4][C:3]=1[O:19][CH2:21][C:22]([O:24][CH3:25])=[O:23]

Participants

Reactant 2

HCID 60984Methyl bromoacetate

HCID 127740892-Phenyl-5-hydroxy-6,7-dichloro-1-indanone

Product 1

HCID 12774096Methyl (6,7-dichloro-1-oxo-2-phenyl-5-indanyloxy)acetate

Procedure

Reaction of 6,7-dichloro-5-hydroxy-2-phenyl-1-indanone with methyl bromoacetate according to the procedure of Example 1, STEP (a), affords the title compound, m.p. 151.5°-153° (from benzenecyclohexane).

Sources & evidence

ORD record: ord-0db22fb8bcdd41758e5320a5192819d4
Source dataset: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04334088

Reaction notes

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