HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-1-(trimethylsilyl)-1-propyne → Ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-2-(3-(trimethylsilyl)-2-propynyl)-5-indanyloxy]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-1-(trimethylsilyl)-1-propyne | HCID 642589 | — |
| Reactant | Ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-5-indanyloxy]acetate | HCID 12774097 | — |
| Product | Ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-2-(3-(trimethylsilyl)-2-propynyl)-5-indanyloxy]acetate | HCID 12774093 | — |
Reaction Steps
Reaction of ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-5-indanyloxy]acetate with 1-bromo-3-(trimethylsilyl)-2-propyne according to the procedure of Example 1, STEP (b), affords the title compound, m.p. 103°-103.5°; purified by chromatography (silica-gel column eluted with chloroform-n-hexane) and crystallization from ether-cyclohexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04334088 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-92bc5f380fda4207a6da8f07e5b0ef9b |
| Source note | uspto-grants-1982_06 |