4-Chlorophenol → HCID 532464, compound

HRID 1156203Notes

Reaction equation

HRID 1156203 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[Cl:9][C:10]([Cl:15])([Cl:14])[C:11](Cl)=[O:12]>>[Cl:9][C:10]([Cl:15])([Cl:14])[C:11]([O:8][C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)=[O:12]

Participants

3

Reactant 2

HCID 46844-ChlorophenolHCID 6420Trichloroacetyl chloride

Product 1

HCID 532464HCID 532464, compound

Conditions

Temperature
120 °C

Procedure

A 25.6 gram (g) (0.2 mole) sample of 4-chlorophenol was mixed with 40 g of trichloroacetyl chloride at room temperature. The resulting solution was heated under reflux conditions at 120° C. for 10 hours. The temperature was gradually increased to 180° C. over a period of 16 hours. The reaction mixture was then allowed to cool to room temperature. An insoluble solid product was collected by filtration and dried in vacuo. The solid was identified by vapor phase chromatography as 4-chlorophenyl trichloroacetate.

Workup

  1. temperatureThe temperature was gradually increased to 180° C. over a period of 16 hours
  2. temperatureto cool to room temperature
  3. filtrationAn insoluble solid product was collected by filtration
  4. customdried in vacuo

Sources & evidence

ORD record
ord-3d2d4000b5304d2baf2193d4ffa8ccbe
Source dataset
uspto-grants-1982_06
Patent number
US04334111

Reaction notes

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