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Water → N-(1-cyano-1,2-dimethylpropyl)-2,3-Dibromopropionamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 2,3-Dibromopropanoyl chloride | HCID 86790 | — |
| 反応物 | 2,3-Dimethyl-2-aminobutyronitrile hydrochloride | HCID 12945444 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N-(1-cyano-1,2-dimethylpropyl)-2,3-Dibromopropionamide | HCID 12945446 | — |
反応手順
A mixture of 4.5 g (0.03 mole) of the 2,3-dimethyl-2-aminobutyronitrile hydrochloride, 4.8 g (0.06 mole) of 50% aqueous sodium hydroxide, 15 ml of dichloromethane and 15 ml of water was prepared. A second solution of 7.5 g (0.03 mole) of 2,3-dibromopropionyl chloride in 15 ml dichloromethane was added with rapid stirring to the first mixture at 10°-15° C. The mixture was then allowed to reach room temperature.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04335053 |
| 出典データセット | uspto-grants-1982_06 |
| ORD ID | ord-ba09355c1cf44c339cc5a238e027a803 |
| 出典メモ | uspto-grants-1982_06 |