HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → (4-Piperidinyl)(2-thienyl)methanone hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | HCID 20278951 | HCID 20278951 | — |
| Solvent | Water | HCID 962 | — |
| Product | (4-Piperidinyl)(2-thienyl)methanone hydrobromide | HCID 20278974 | 85% |
Reaction Steps
A mixture of 20 parts of ethyl 4-(2-thienylcarbonyl)-1-piperidinecarboxylate and 120 parts of hydrobromic acid solution 48% in water is stirred and refluxed for 2 hours. The reaction mixture is cooled and the precipitated product is filtered off. It is washed with 2-propanol and dried, yielding 17 parts (85%) of (4-piperidinyl) (2-thienyl)methanone hydrobromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04335127 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-052abbf73ef946a6b8b8ae7b5de3c00b |
| Source note | uspto-grants-1982_06 |