Acetonitrile → 4-(5-Phenyl-pyrimidin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[O:18][C:19](=[O:20])[N:21]1[CH2:22][CH2:23][CH:24]([NH2:27])[CH2:25][CH2:26]1.[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[CH3:35][C:36]#[N:37].[Cl:1][c:2]1[n:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:6][n:7]1>>[c:2]1([NH:27][CH:24]2[CH2:23][CH2:22][N:21]([C:19]([O:18][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:20])[CH2:26][CH2:25]2)[n:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:6][n:7]1Participants
5
Sources & evidence
- ORD record
- ord-7fd136ae657c4c4e85eb38a0064f424a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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