Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethylmorpholine | HCID 7525 | — |
| Reactant | Acrylonitrile | HCID 7855 | — |
| Reactant | 4-Formylbenzoyl chloride | HCID 12424620 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | Anisole | HCID 7519 | — |
| Product | HCID 54377318 | HCID 54377318 | 52% |
Reaction Steps
0.0018 g (0.008 millimol) of palladium acetate, 6.74 g (40 millimols) of 4-formylbenzoyl chloride, 3.29 g (50 millimols) of acrylonitrile and 5.12 ml (40 millimols) of N-ethylmorpholine are added to 80 ml of anisole. The mixture is stirred for 12 hours at 120° C., under argon. The crude product is distilled in vacuo and is then recrystallised from isopropanol. 3.2 g (52% of theory) of 4-formylcinnamonitrile are obtained in the form of white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04335054 |
|---|
| Source dataset | uspto-grants-1982_06 |
|---|
| ORD ID | ord-50fd0df2de054cd5a9f01846ffd56c0f |
|---|
| Source note | uspto-grants-1982_06 |
|---|
