反应详情

温度

120 °C

0.0018 g (0.008 millimol) of palladium acetate, 6.74 g (40 millimols) of 4-formylbenzoyl chloride, 3.29 g (50 millimols) of acrylonitrile and 5.12 ml (40 millimols) of N-ethylmorpholine are added to 80 ml of anisole. The mixture is stirred for 12 hours at 120° C., under argon. The crude product is distilled in vacuo and is then recrystallised from isopropanol. 3.2 g (52% of theory) of 4-formylcinnamonitrile are obtained in the form of white crystals.

1. distillationThe crude product is distilled in vacuo
2. customis then recrystallised from isopropanol