反应详情

A mixture of 5-(2,4-dichlorophenyl)-2-furancarboxaldehyde (635 g, 2.63 moles), anhydrous sodium acetate (432 g, 5.26 moles), hydroxylamine hydrochloride (366 g, 5.26 moles), SDA #30 (9184 ml) and water (918 ml), was refluxed for 51/3 hours and allowed to stand overnight. The mixture was added to ice/H2O (42 liters), stirred 1 hour and filtered. The grayish-tan solid was washed with water (10 liters), filtered and dried at 65° to 660 g (98%).

1. temperaturewas refluxed for 51/3 hours
2. filtrationfiltered
3. washThe grayish-tan solid was washed with water (10 liters)
4. filtrationfiltered
5. customdried at 65° to 660 g (98%)