Guanidine → HCID 178512730, compound

HRID 1156507Notes

Reaction equation

HRID 1156507 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[C:6]([Cl:11])[N:5]=[CH:4][N:3]=1.[NH2:12][C:13]([NH2:15])=[NH:14]>C(O)C>[NH:14]([C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[C:6]([Cl:11])[N:5]=[CH:4][N:3]=1)[C:13]([NH2:15])=[NH:12]

Participants

4

Reactant 2

HCID 3520GuanidineHCID 203124,6-Dichloro-5-nitropyrimidine

Product 1

HCID 178512730HCID 178512730, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 10 g of 4,6-dichloro-5-nitropyrimidine in ethanol is reacted at reflux for three days with a slight excess of guanidine to give 4-guanidino-6-chloro-5-nitropyrimidine.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-049dacb4a1684082b70ebc0541e4c625
Source dataset
uspto-grants-1982_06
Patent number
US04336255

Reaction notes

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