HCID 56610644, compound → HCID 20534813, compound

Participants

Reaction Steps

16 g (0.045 mole) of 4-benzyl-9a-(3-methoxyphenyl)-perhydro-1,4-benzoxazepine (boiling point 240°-260° C./0.07 mbar), prepared by methods similar to that of Example 1, are hydrogenated in the conventional manner with a palladium/charcoal catalyst (5 g of 5% strength Pd on charcoal) in glacial acetic acid; after filtration and distillation, 8.8 g (75% of theory) of 9a-(3-methoxyphenyl)-perhydro-1,4-benzoxazepine, of boiling point 180°-185° C./0.07 mbar, are obtained.

Provenance & Evidence