HCID 178473465, compound → HCID 86737832, compound

HRID 1156622Notes

Reaction equation

HRID 1156622 reaction equation
[N:1]1([C:7]2[N:12]=[C:11]([NH:13][C:14](OCC)=[O:15])[N+:10]([O-:19])=[C:9]([NH:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])[N:8]=2)[CH2:6][CH:5]=[CH:4][CH2:3][CH2:2]1>CN(C)C=O>[N:1]1([C:7]2[N:8]=[C:9]([NH:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])[N:10]3[O:19][C:14](=[O:15])[N:13]=[C:11]3[N:12]=2)[CH2:6][CH:5]=[CH:4][CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 178473465HCID 178473465, compound

Product 1

HCID 86737832HCID 86737832, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

4.8 g. of diethyl 6-[3,6-dihydro-1(2H)-pyridyl]-s-triazin-2,4-dicarbamate-3-oxide are mixed with 100 ml. of absolute dimethylformamide and stirred at 140° C. for 30 minutes. The solvent is then evaporated off under reduced pressure and the residue is recrystallized from methylene chloride and diethyl ether, there being obtained pure ethyl 5-[3,6-dihydro-1(2H)-pyridyl]-2-oxo-2H-[1,2,4]oxadiazolo[2,3-a]-s-triazine-7-carbamate having a melting point of 220°-225° C. (decomposition).

Workup

  1. customThe solvent is then evaporated off under reduced pressure
  2. customthe residue is recrystallized from methylene chloride and diethyl ether, there

Sources & evidence

ORD record
ord-b0a19218a731461da8ba64cbf783c615
Source dataset
uspto-grants-1982_06
Patent number
US04336380

Reaction notes

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