HRID1156717

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6420

Trichloroacetyl chloride

C2Cl4O

HCID13150493

N-Methyl-3-(trichloromethyl)-1,2,4-thiadiazol-5-amine

C4H4Cl3N3S

PRODUCTS

生成物

结构：CN(C(=O)C(Cl)(Cl)Cl)c1nc(C(Cl)(Cl)Cl)ns1

HCID12851602

未命名化合物

收率 92%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1140

Toluene

C7H8

CONDITIONS

反应条件

温度: -10 °C

PROCEDURE

实验过程

A solution of 5.8 grams (0.02 mole) 5-methylamino-3-trichloromethyl-1,2,4-thiadiazole and 9.0 grams (0.05 mole) trichloroacetyl chloride in 200 milliliters toluene was refluxed at about 110° C. for 20 hours. Upon cooling to -10° C., 2.7 grams pure product precipitated; m.p. 223° C. An additional 6.0 grams product was isolated by removal of the low boiling materials in vacuo. Total yield was 92%.

WORKUP

后处理

custom2.7 grams pure product precipitated