HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 12851604, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 3-(Trifluoromethyl)-1,2,4-thiadiazol-5-amine | HCID 20533652 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 12851604 | HCID 12851604 | 55% |
Reaction Steps
A solution of 4.3 grams (0.05 mole) 5-amino-3-trifluoromethyl-1,2,4-thiadiazole and 7.0 grams (0.09 mole) acetyl chloride in 50 milliliters xylene was refluxed at about 140° C. for 20 hours. Upon cooling to room temperature 2.9 grams (55% yield) pure product precipitated; m.p. 178.1° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337081 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-8eb2c057cda341d8a5c33af5de18b25e |
| Source note | uspto-grants-1982_06 |