Potassium Hydroxide → HCID 136061479, compound

Participants

Reaction Steps

To a solution of potassium hydroxide (2.02 g) in a mixture of ethanol (50 ml) and water (10 ml), 5-benzylthio-2,3-dihydro-1,2,4-triazin-3-one (6.58 g) and hydroxylamine sulfate (2.95 g) were added, and the resultant mixture was refluxed for 5 hours. The reaction mixture was cooled to room temperature and concentrated under reduced pressure. The residue was recrystallized from water to give 5-hydroxyamino-3-oxo-2,3-dihydro-1,2,4-triazine (Ic) (3.34 g) as pale yellow crystals. Yield, 87.1%.

Provenance & Evidence