HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53908529, compound → HCID 53869724, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53908529 | HCID 53908529 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 53869724 | HCID 53869724 | — |
Reaction Steps
A mixture of 4.0 g 3-(4-chloro-N-methyl-2-nitrophenylamino)-pyrazine-2-carboxylic acid methyl ester, 200 ml ethyl acetate and 4 g Raney Nickel are hydrogenated at room temperature under normal pressure. The catalyst is removed by filtration and the filtrate is evaporated to afford the heading compound. It is used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337198 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-2c2e967c719142e19c74d0821f2f409b |
| Source note | uspto-grants-1982_06 |