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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1156750Generated: October 30, 2026

Acrylonitrile → Mls003106934

https://huagongshe.com/reaction/1156750

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcrylonitrileHCID 7855—
Reactant(Morpholin-4-yl)(pyridin-3-yl)acetonitrileHCID 303572—
ProductMls003106934HCID 301902—

Reaction Steps

Leete et al. [J. Org. Chem. 37, 4465-6 (1972)] shows the reaction of 2-(3-pyridinyl)-2-(4-morpholinyl)ethanenitrile with acrylonitrile to produce 4-cyano-4-(3-pyridinyl)-4-(4-morpholinyl)butanenitrile and its conversion by heating it with acetic acid, water and tetrahydrofuran to 4-oxo-4-(3-pyridinyl)butanenitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04337253
Source datasetuspto-grants-1982_06
ORD IDord-648ea2fc8cff43e3a6a16eb5b4bf882b
Source noteuspto-grants-1982_06