HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-1,2-dihydro-2-oxocyclohepta[b]pyrrole-3-carboxylic acid ethyl ester → 6-Chloro-1,2-dihydro-2-oxocyclohepta[b]pyrrole-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-1,2-dihydro-2-oxocyclohepta[b]pyrrole-3-carboxylic acid ethyl ester | HCID 12852678 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 6-Chloro-1,2-dihydro-2-oxocyclohepta[b]pyrrole-3-carboxylic acid | HCID 12852687 | — |
Reaction Steps
6-Chloro-1,2-dihydro-2-oxocyclohepta[b]pyrrole-3-carboxylic acid ethyl ester (1.0 g, described in example 9) was hydrolyzed with 2 N aqueous NaOH (20 ml) under the conditions described for the hydrolysis in example 14 to give 6-chloro-1,2-dihydro-2-oxocyclohepta[b]pyrrole-3-carboxylic acid; mp 227° C. (dec); nmr (DMSO-d6) δ7.39-9.8 (m, 4H), 12.4 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337265 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-46ce011c966d4dc1a71111239d2fe3e9 |
| Source note | uspto-grants-1982_06 |