Chlorosuccinimide → HCID 12851836, compound

HRID 1156877Notes

Reaction equation

HRID 1156877 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[C:13]([CH3:18])[CH:14]=[CH:15][CH:16]=3)[CH:11]=[CH:10][N:9]=2)=[CH:4][CH:3]=1.[Cl:19]N1C(=O)CCC1=O>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[C:13]([CH2:18][Cl:19])[CH:14]=[CH:15][CH:16]=3)[CH:11]=[CH:10][N:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 31398ChlorosuccinimideHCID 128518351-(4-Fluorophenyl)-5-methylisoquinoline

Product 1

HCID 12851836HCID 12851836, compound

Procedure

1-(4-Fluorophenyl)-5-methylisoquinoline was reacted with N-chlorosuccinimide in the same way as in step (a) of Example 2 to afford 1-(4-flurophenyl)-5-chloromethylisoquinoline as colorless needles having a melting point of 109.5° to 111.5° C.

Sources & evidence

ORD record
ord-a359f9b13b77468893868f6196cf1a24
Source dataset
uspto-grants-1982_06
Patent number
US04337256

Reaction notes

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