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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1156878Generated: October 31, 2026

Sodium Cyanide → 1-(4-Flurophenyl)isoquinoline-5-acetonitrile

https://huagongshe.com/reaction/1156878

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CyanideHCID 8929—
ReactantHCID 12851836HCID 12851836—
Product1-(4-Flurophenyl)isoquinoline-5-acetonitrileHCID 12798961—

Reaction Steps

Sodium cyanide and 1-(4-fluorophenyl)-5-chloromethylisoquinoline were reacted in the same way as in step (b) in Example 2 to afford 1-(4-flurophenyl)isoquinoline-5-acetonitrile having a melting point of 136° to 136.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04337256
Source datasetuspto-grants-1982_06
ORD IDord-1019ff16f32548b1a9af4579007a1d27
Source noteuspto-grants-1982_06