HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-5-methoxycarbonylisoquinoline → 1-n-Propylisoquinoline-5-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-5-methoxycarbonylisoquinoline | HCID 12851848 | — |
| Reactant | HCID 12851849 | HCID 12851849 | — |
| Product | 1-n-Propylisoquinoline-5-acetonitrile | HCID 20533873 | — |
Reaction Steps
1-Amino-2-(2-hydroxymethylphenyl)ethane and butyryl chloride were successively reacted in the same way as in steps (b) and (c) of Example 12 to afford 1-butyrylamino-2-(2-hydroxymethylphenyl)ethane as an oil. The product was successively reacted in the same way as in steps (d), (e), (f) and (g) of Example 12 to afford 1-n-propylisoquinoline-5-acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337256 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-c4c04884ced14733941523b6c5a1de4e |
| Source note | uspto-grants-1982_06 |