Ethanol → HCID 53943974, compound

Participants

Reaction Steps

1-iso-Propylisoquinoline-5-acetic acid (0.5 g) was dissolved in 20 ml of ethanol, and 3 ml of conc. sulfuric acid was added. The mixture was heated under reflux for 3 hours. The reaction mixture was poured into ice water, made weakly alkaline with potassium carbonate, extracted with benzene, washed in water, and dried. The solvent was distilled off under reduced pressure to afford 0.5 g of ethyl 1-isopropylisoquinoline-5-acetate as a colorless oil.

Provenance & Evidence