2-Chlorobenzoyl chloride → HCID 12851811, compound

Participants

Reaction Steps

1-Amino-2-(2-methylphenyl)ethane and 2-chlorobenzoyl chloride were reacted in the same way as in step (a) of Example 1 to afford 1-(2-chlorobenzoyl)amino-2-(2-methylphenyl)ethane having a melting point of 90.4° to 90.9° C. The product was successively reacted in the same way as in steps (b), (c), (d) and (e) to afford 1-(2-chlorophenyl)isoquinoline-5-acetonitrile having a melting point of 112.8° to 113.3° C.

Provenance & Evidence