4-Toluenesulfonyl chloride → (2-Methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-5-yl)methyl 4-methylbenzene-1-sulfonate

HRID 1156961Notes

Reaction equation

HRID 1156961 reaction equation
[C:1]1([CH3:11])[CH:6]=[CH:5][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[CH3:12][C:13]1[S:14][C:15]2[CH2:21][CH2:20][CH:19]([CH2:22][OH:23])[CH2:18][C:16]=2[N:17]=1>>[CH3:12][C:13]1[S:14][C:15]2[CH2:21][CH2:20][CH:19]([CH2:22][O:23][S:7]([C:4]3[CH:5]=[CH:6][C:1]([CH3:11])=[CH:2][CH:3]=3)(=[O:9])=[O:8])[CH2:18][C:16]=2[N:17]=1

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 3018726(2-Methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-5-yl)methanol

Product 1

HCID 3018727(2-Methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-5-yl)methyl 4-methylbenzene-1-sulfonateYield 74%

Procedure

The compound is prepared by action of p-toluenesulfonyl chloride on the above alcohol (IV), according to the procedure described in Example 1. M.p.=105°-106° C. Yield: 74%.

Sources & evidence

ORD record
ord-b2f69c1ae18140b485757da1d015002c
Source dataset
uspto-grants-1982_06
Patent number
US04337343

Reaction notes

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